Competing endogenous rna翻译

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August undefined, 2024

WebJan 30, 2014 · The discovery of microRNAs (miRNAs) has led to a paradigm shift in our basic understanding of gene regulation. Competing endogenous RNAs (ceRNAs) are … Web活细胞RNA技术在mRNA翻译研究领域的应用. 翻译是在细胞核中DNA转录为RNA后，细胞质或内质网中核糖体合成蛋白质的过程。研究者将RNA成像技术与Suntag荧光扩增技术（标记新生肽链）相结合，巧妙地在单分子水平上对蛋白质翻译动态进行解析。

消化系统恶性肿瘤中ceRNA的研究进展_参考网

WebJan 30, 2014 · Competing endogenous RNAs (ceRNAs) are the recent entrants adding to the complexities of miRNA mediated gene regulation. ceRNAs are RNAs that share miRNA recognition elements (MREs) thereby regulating each other. It is apparent that miRNAs act as rheostats that fine-tune gene expression and maintain the functional balance of … WebThe competing endogenous RNA (ceRNA) hypothesis describes control of gene function through regulating miR accessibility to targets by sequestering sequences. The … knights hill surgery west norwood

ceRNA（竞争性内源RNA）：国自然基金热点领 …

WebJan 10, 2024 · MicroRNAs (miRNAs) are post-transcriptional regulators with potential as biomarkers for cancer management. Data-driven competing endogenous RNA … WebJan 21, 2024 · 非编码 rna pirna mirna mir sirna. 非编码RNA的分类及概念分类非编码RNA (non—codingRNA）是指转录组中不翻译为蛋白质的RNA分子。. 包括相对分子量较小的核内小分子RNA (smallnuclearRNA，snRNA)、核仁小分子RNA (smallnucleolarRNAs,snoRNA）、微RNA (microRNA，miRNA)、piwi-interactingRNA … WebJan 19, 2024 · RNAs may act as competing endogenous RNAs (ceRNAs), a critical mechanism in determining gene expression regulations in many cancers. However, the roles of ceRNAs in thyroid carcinoma remains elusive. In this study, we have developed a novel pipeline called Molecular Network-based Identification of ceRNA (MNIceRNA) to identify … red crab juicy seafood cville

Competing endogenous RNAs: a target-centric view of small RNA …

Frontiers Competing endogenous RNAs (ceRNAs): new entrants …

WebFeb 2, 2014 · Competing endogenous RNA, ceRNA, vie with messenger RNAs (mRNAs) for microRNAs (miRNAs) with shared miRNAs responses elements (MREs) and act as … WebSep 19, 2016 · Similarly to competing endogenous RNAs (ceRNAs) in mammalian cells, competition for regulatory RNAs and proteins can lead to crosstalk between bacterial … knights hill west norwoodWebceRNA (Competing endogenous RNA, 内源竞争性 RNA)，通常指 mRNA、lncRNA、circRNA 等 RNA 分子，竞争性结合 miRNA 的作用方式。当 miRNA 被 lncRNA 或 … knights hockey london

"WebAug 12, 2024 · ceRNA 不同于mRNA, lncRNA, ncRNA 等概念，其指的既不是某一种类型的RNA(比如mRNA, lncRNA), 也不是某一类的RNA(如ncRNA); ceRNA 其实指的是不同种类的RNA之间的调控机制，英文名为 competing endogenous RNA , 翻译成中文叫做 " 竞争性内源RNA "; 在这个概念中有两个关键词，竞争和 ... " - Competing endogenous rna翻译

Competing endogenous rna翻译

Web曹金玉，张德元，刘繁荣. 竞争性内源性RNA(competing endogenous RNA, ceRNA)假说是由美国哈佛大学医学院Salmena等[1]首先提出，该假说认为lncRNA、mRNA、假基因转录物、环状RNA等各类RNA分子，仅需相同的miRNA应答元件，就能竞争性结合相同的miRNA来调控靶基因，从而调节各自的表达，进一步影响肿瘤细胞的增殖 ... WebKeywords: Competing endogenous RNA, eukaryotic genome, gene expression, miRNA sponges. During the last half a century, studies on plant and ani mal genomes have witnessed many surprises. One of the early surprises in late 1960s was the discovery of high proportion of repetitive and noncoding DNA (ncDNA) in majority of eukaryotic genomes.

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Web2011年提出了竞争性内源RNA（competing endogenous RNA，ceRNA）假说，认为LncRNA 可以发挥海绵效应，通过miRNA 应答原件（miRNA response elements，MREs）竞争性结合miRNA 进行交流，相互调控各自的表达水平，从而构成庞大的调节网络，减弱对下游基因表达的直接影响[13 ... WebSep 14, 2015 · The existence of artificial sponges and antisense oligonucleotides designed to decrease the availability of microRNAs (miRNAs), a family of small non‑coding RNAs that target RNA transcripts through miRNA response elements (MREs) involved in gene expression, suggests that miRNAs may also be regulated. The wide range of RNA …

WebThe hypothesis of "competing endogenous RNA (ceRNAs)" is one of the most fascinating areas of recent research. ceRNAs, including long noncoding RNA (lncRNA), circular … WebThis concept is a new area of ongoing research recognized as competing endogenous RNA (ceRNA) hypothesis. CeRNAs are novel regulatory molecules in a wide range of …

WebDec 3, 2015 · Pandolfi等人提出了ceRNA（competing endogenous RNA，竞争性内源RNA）的假说，认为这种ceRNA活性能形成一种大规模转录调控网络，可以扩大人类基因组中的功能性遗传信息。. 他们认为这种 … In molecular biology, competing endogenous RNAs (abbreviated ceRNAs) regulate other RNA transcripts by competing for shared microRNAs (miRNAs). Models for ceRNA regulation describe how changes in the expression of one or multiple miRNA targets alter the number of unbound miRNAs and lead to … See more MicroRNAs are an abundant class of small, non-coding RNAs (~22nt long), which negatively regulate gene expression at the levels of messenger RNAs (mRNAs) stability and translation inhibition. The human genome contains … See more • Competing endogenous RNA (ceRNA) databases and resources • StarBase (biological database), ceRNA database • Gene expression See more Two studies by Bosson et al. (2014) and Denzler et al. (2014) have empirically assessed the ceRNA hypothesis by quantifying the … See more High-throughput validation of ceRNA regulatory networks Chiu et al. used LINCS data to support the regulation of hundreds of genes by ceRNA interactions in prostate and breast adenocarcinomas. The PTEN ceRNA … See more • ceRNABase: Pan-Cancer ceRNA regulatory networks from CLIP-Seq experimentally supported miRNA target sites and thousands of tumor samples • Cupid: simultaneous reconstruction of microRNA-target and ceRNA networks See more

WebSep 12, 2024 · 摘要: 竞争性内源RNA（competing endogenous RNA，ceRNA）是一种新的转录后RNA相互调控机制，越来越多的研究发现长链非编码RNA（long non-coding RNA，lncRNA）、环状RNA（circular RNA，circRNA）和假基因（pseudogenes）可以与微小RNA（microRNA，miRNA）竞争，影响靶RNA的稳定性或翻译 ...

WebFeb 22, 2024 · The competitive endogenous RNA (ceRNA) theory, first proposed by Salmena et al, is largely accepted by the scientific community. [ 6 ] lncRNAs can function in the ceRNA network as endogenous molecular sponges of miRNAs and indirectly control the production of messenger RNAs. red crab juicy seafood waterbury cthttp://www.xdzlyx.com/oa/DArticle.aspx?id=202420033 red crab juicy seafood indian harbor beachWebJan 28, 2024 · Competing endogenous RNA (ceRNA) is a group of different RNAs that compete with mRNA for the same pool of micro RNAs (miRNA). In doing this they … knights holidays kessinglandWebCupid is a method for simultaneous prediction of miRNA-target interactions and their mediated competing endogenous RNA (ceRNA) interactions. It is an integrative … knights hill surgery se27WebLncRNA作为RNA三宝（miRNA、lncRNA和circRNA）之一，是一类长度超过200nt的非编码RNA分子，其缺乏开放阅读框（ORF），无编码蛋白质功能，迄今为止，国内外学者依然热衷于lncRNA的生物学功能研究。. 近5年来，lncRNA相关文章发表量直线上升，并依然可作为RNA功能研究的 ... knights hockeyWebAug 1, 2024 · The competing endogenous RNA (ceRNA) theory states that ceRNAs, including mRNAs, lncRNAs and other miRNAs sponges, share common miRNA binding sites, and consequently they can function as molecular sponges for miRNAs because of the limited amount of a given miRNAs (Salmena et al. 2011). red crab juicy seafood pyramid villageWebed a comprehensive analysis of ceRNA network and constructed a mRNA signature to predict prognosis of pRCC. We collected mRNAs and lncRNAs expression profiles of … red crab juicy seafood whitehall pa